Feature

Systematic Reviews and Meta-Analyses — Literature-based Recommendations for Evaluating Strengths, Weaknesses, and Clinical Value

Abstract

Good quality systematic reviews (SRs) summarizing best available evidence can help inform clinical decisions, improving patient and wound outcomes. Weak SRs can misinform readers, undermining care decisions and evidence-based practice....

Manual Lymph Drainage in a Patient with Congestive Heart Failure: A Case Study

Abstract

A variety of conditions result in lower extremity edema, such as deep vein thrombosis, cellulitis, venous stasis insufficiency, and congestive heart failure (CHF). A case study is presented to illustrate the dynamics of the lymphatic system, the pathology of CHF, the importance of obtaining a pretreatment differential diagnosis, and how to implement a safe treatment plan. ...

Use of a Dehydrated Amniotic Membrane Allograft on Lower Extremity Ulcers in Patients with Challenging Wounds: A Retrospective Case Series

Abstract

Lower extremity ulcers in patients with diabetes mellitus may take a long time to heal despite the use of advanced topical therapies. A retrospective review of cases was conducted to assess the use of a dehydrated amniotic membrane allograft (DAMA) in a convenience sample of 9 wounds in 8 patients (5 men, 3 women, average age 62 years [range 31–81 years]) with diabetes mellitus and/or vascular disease. ...

A Prospective, Multicentered Study to Assess Social Adjustment in Patients With an Intestinal Stoma in Turkey

Abstract

Patients with a stoma undergo physiological, psychological, and social adjustment to their new life situation. A descriptive, prospective study was conducted to assess adaptation among patients >18 years of age with a new temporary or permanent colostomy or ileostomy living in Turkey and receiving care at a participating stomatherapy unit. ...

Dehydrated Human Amnion/Chorion Membrane as Adjunctive Therapy in the Multidisciplinary Treatment of Pyoderma Gangrenosum: A Case Report

Abstract

Pyoderma gangrenosum (PG) is an uncommon chronic and progressive skin disorder that can lead to severe tissue necrosis, pathergy, horrendous pain, and disfigurement if not properly and promptly diagnosed and treated. Systemic treatment traditionally consists of long-term immunosuppression. Topical care of the painful wound often represents a clinical challenge. ...

Adverse Effect of Sildenafil on Healing Ischemic Wounds: Results of an In vivo Study

Abstract

Phosphodiesterase-5 is an enzyme that inactivates cyclic guanosine monophosphate and regulates the balance of nitric oxide (NO). NO is an important molecule synthesized during wound repair. ...

A Retrospective Analysis of Pressure Ulcer Incidence and Modified Braden Scale Score Risk Classifications

Abstract

The Braden Scale is the most widely used pressure ulcer risk assessment in the world, but the currently used 5 risk classification groups do not accurately discriminate among their risk categories. To optimize risk classification based on Braden Scale scores, a retrospective analysis of all consecutively admitted patients in an acute care facility who were at risk for pressure ulcer development was performed between January 2013 and December 2013. ...

A Skin-stretching Wound Closure System to Prevent and Manage Dehiscence of High-tension Flap Donor Sites: A Report of 2 Cases

Abstract 

Tension on the suture line of flap donor sites raises the risk of delayed healing and wound dehiscence. Closing a large flap donor site without a skin/flap graft is a major surgical challenge. ...

Assessing the Validity and Reliability of the Peristomal Skin Lesion Assessment Instrument Adapted for Use in Turkey

Abstract

Many ostomy patients experience peristomal skin lesions. A descriptive study was conducted to assess the validity, usability, and reliability of the Peristomal Skin Lesions Assessment instrument (SACS instrument) adapted to Turkish from English. The SACS Instrument consists of 2 main assessments: lesion type (utilizing definitions and photographs) and lesion area by location around the ostomy....

An In vivo Wound Model Utilizing Bacteriophage Therapy of Pseudomonas aeruginosa Biofilms

Abstract 

Bacteriophages have been used as effective therapy against bacterial biofilms on devices such as catheters, in the lungs such as in cystic fibrosis, and even in infected food. Unlike antibiotics, they are bacteria-specific and produce the desired effect without systemic complications; they can develop bacterial resistance, although in ways different from antibiotics....