Offloading Difficult Wounds and Conditions in the Diabetic Patient
- Wed, 9/3/08 - 10:24am
- 0 Comments
- 11912 reads
Lower extremity wounds represent significant medical and financial challenges to the healthcare system. This is especially the case in the diabetic population where neuropathy, often associated with vascular disease, can lead to ulceration, immobility, infection, and gangrene. One study places the average cost of healing a single diabetic ulcer at approximately $36,000,1 leading to direct costs of $600 million dollars annually.2 Limitations on mobility caused by foot ulcers have a negative impact on social, psychological, physical, and economic domains.3 Charcot arthropathy can create additional complications; all of these sequelae can lead to major limb amputation.1 Early recognition and prompt management of these foot ulcers can facilitate healing.4 Additional data suggest that meticulous, scientifically based wound care and patient education strategies can reduce lower extremity amputation rates by reducing the frequency and severity of foot ulcers.5
In response to the high costs of managing chronic wounds, systems of comprehensive outpatient care have been established and represent an interdisciplinary and collaborative approach to wound management. The goals of wound care protocols are to treat underlying conditions that cause wounds, facilitate the wound healing process, and minimize skin breakdown and wound recurrence.6 The scope of potential interventions includes debridement, infection control, offloading, protective and active dressings, revascularization, proper nutrition, and patient education.7 Offloading is important for reducing foot pressure points8 and for prevention,9 as well as for healing.10
The following article discusses offloading difficult wounds and Charcot foot at various stages of treatment and prevention. The pedorthic management of foot amputations also will be discussed.
The Neuropathic Ulcer
The main cause of foot ulceration is neuropathy (see Figure 1).11 This leads to prolonged and excessive pressures that cause tissue breakdown. Using footwear as a means of healing open wounds is rarely desirable.12 Currently, total contact casting (TCC) (see Figure 2) represents the gold standard for the treatment of forefoot and midfoot (Wagner grade 1-2) diabetic and neuropathic ulcerations; however, reduction of heel pressures with this device remains controversial. Myerson et al13 estimate that 6 weeks of treatment in a total contact cast costs the same as a single day of inpatient treatment. Specialized casting protects the foot from trauma, immobilizing skin edges and reducing edema. It decreases pressure over the ulcer by redistributing the weightbearing load over a greater plantar surface area.
Molding the bottom of the cast to the bottom of the foot causes the entire sole to participate in the force distribution, resulting in lower pressures.14 In 1985, Birke et al15 reported 75% to 84% reduction of peak pressure at the first and third metatarsal heads, respectively, when subjects walked in a cast. Many other studies have supported the successful rationale for TCC use. For example, Sinacore et al16 noted healing in 82% of 33 ulcers after an average of 44 days in a total contact cast. Myerson et al13 observed healing in 64 out of 71 (90%) ulcers at a mean of 5.5 weeks. Hanft et al17 performed a 10-year retrospective study utilizing total contact casts on more than 1,000 patients. The research demonstrated a healing rate of 91% within 13 weeks with an average closure time of 4.36 weeks (± 1.31 weeks). It was concluded that the total contact cast was an effective, low-risk, and inexpensive treatment for plantar diabetic foot ulcers.
1. Greene DA, Feldman EL, Stevens M. Neuropathy in the diabetic foot: new concepts in etiology and treatment. In: Levin ME, O?Neil LW, Bowker JH, eds. The Diabetic Foot, 5th ed. St. Louis, Mo.: Mosby Year Book; 1993. 2. Jiwa F. Diabetes in the 1990s. An overview. Stat Bull Metro Insurance Company. 1997;78:2-8. 3. Brod M. Quality of life in patients with diabetes and lower extremity ulcers: patients and caregivers. Qual Life Res. 1998;7:365-372. 4. American Diabetes Association. Position statement; foot care in patients with diabetes mellitus. Diabetes Care. 1995;18(suppl 1):S26-S27. 5. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Prevention and early intervention for diabetes foot problems. Feet Can Last a Lifetime. Bethesda, Md.: NIDDK; 1998. 6. Glover JL, Weingarten MS, Buchbinder DS, et al. A 4-year outcome-based retrospective study of wound healing and limb salvage in patients with chronic wounds. Advances in Wound Care. 1997;10:33-38. 7. Steed DL, Donohoe D, Webster MW, et al. Effect of extensive debridement and treatment on the healing of diabetic foot ulcers. J Am Coll Surg. 1996;183:61-64. 8. Boulton AJM. The diabetic foot. Med Clin North Am. 1988;72(6):1513-1530. 9. Janisse DJ. Prescription insoles and footwear. Clin Pod Med Surg. 1995;12:41-61. 10. Lavery LA, Vela SA, Lavery DC, et al. Reducing dynamic foot pressures in high-risk diabetic subjects with foot ulcerations: a comparison of treatments. Diabetes Care. 1996;19:818-821. 11. Levin ME. Preventing amputations in the patient with diabetes. Diabetes Care. 1995;18:1383-1392. 12. Coleman WC, Brand PW, Birke JA. The total contact cast. J Am Podiatr Assoc. 1984;74:548. 13. Myerson M, Papa J, Eaton K, et al. Total contact casting for the management of neuropathic plantar ulceration of the foot. Amer J Bone Joint Surg. 1992;74A:261-269. 14. Dhawan S, Conti S. Use of total contact casting in the diabetic foot. Foot and Ankle Clinics. 1997;2(1):115-136. 15. Birke JA, Sims DA, Buford WL. Walking casts: effect of plantar foot pressures. J Rehabil Res Dev. 1985; 22:18. 16. Sinacore DR, Meuller MJ, Diamond JE, et al. Diabetic plantar ulcers treated with total contact casting: a clinical report. Phys Ther. 1987;67:1543-1549. 17. Hanft JR, Surprenant MS. Is total contact casting the gold standard for the treatment of diabetic foot ulcerations? Abstract presented at: Joint Annual Meeting and Scientific Seminar; February 9, 2000; Miami, Fla. 18. Lavery LA, Fleischli JG, Laughlin TJ, et al. Is postural instability exacerbated by offloading devices in high-risk diabetics with foot ulcers? Ostomy/Wound Management. 1998;44:26-34. 19. Armstrong DG, Liswood PL, Todd WF. The contra-lateral limb during total contact casting: a dynamic pressure and thermometric analysis. J Am Podiatr Med Assoc. 1995;85;733-737. 20. Armstrong DG, Lavery LA, Harkless LB. Options for off-loading the diabetic foot. Wounds. 2000;12(6 Suppl B):30B-34B. 21. Pollard JP, LeQuesne LP. Method of healing diabetic forefoot ulcers. Br Med J. 1983;286:436-437. 22. Huband MS, Carr JB. A simplified method of total contact casting for diabetic foot ulcers. Contemporary Orthopedics. 1993;26:143-147. 23. Anderson RB, Davis WH. The pedorthic and orthotic care of the diabetic foot. Foot and Ankle Clinics. 1997;2(1):137-151. 24. Ayaso F, Gorgon D, Lui E. Review of treatment modalities in the off-loading of diabetic foot ulcers. Podiatric Medical Review. 2000;6(2):55-59. 25. Hanft JR, Surprenant MS. The use of the fixed ankle walker for the treatment of plantar diabetic foot ulcerations. ACFAS Abstract presented at: Joint Annual Meeting and Scientific Seminar, American College of Foot and Ankle Surgeons; February 8-12, 2000; Miami, Fla. 26. Fleischli JG, Lavery LA, Vela SA, et al. Comparison of strategies for reducing pressure at the site of neuropathic ulcers. J Am Podiatr Assoc. 1997;87:466-472. 27. McDermott JE, ed. The Diabetic Foot. American Academy of Orthopedic Surgeons Monograph series. 1995;17-18. 28. Chantelau E, Breuer U, Leisch AC, Tanudjada T, et al. Outpatient treatment of unilateral diabetic foot ulcers with the ?half-shoes.? Diabet Med. 1993;10:267-270. 29. Hanft JR, Surprenant MS. The use of the custom molded healing sandal for the treatment of plantar diabetic foot ulcerations. ACFAS Abstract presented at: Joint Annual Meeting and Scientific Seminar, American College of Foot and Ankle Surgeons; February 8-12, 2000; Miami, Fla. 30. Rheinstein J, Yanke J, Marzano R. Developing an effective prescription for lower extremity prosthesis. Foot and Ankle Clinics of North America. 1999;4(1):113-138. 31. Guse ST, Alvine FG. Treatment of diabetic foot ulcers and Charcot neuroarthropathy using the patellar tendon-bearing brace. Foot and Ankle. 1997;18(10):675. 32. Baumhauer JF, Wervey R, McWilliams J, et al. A comparison study of plantar foot pressure in a standardized shoe, total contact cast, and prefabricated pneumatic walking brace. Foot Ankle Int. 1997;18:26-33. 33. Hissink RJ, Manning HA, Van Basal JG. The MABAL shoes, an alternative method in contact casting for the treatment of neuropathic diabetic foot ulcers. Foot Ankle Int. 2000;21(4):320-322. 34. Guzman B, Fisher G, Palladino SJ, Stavosky JW. Pressure-removing strategies in neuropathic ulcer therapy. Shoes, Orthoses, and Related Biomechanics, Clinics. Podiatric Medicine and Surgery. 1994;11(2);339-353. 35. Pollo FE, Brodsky JW, Crenshaw SJ, and Kirksky C. Plantar pressures in total contact casting versus a diabetic walking boot. www.bledsoebrace.com. Accessed 11/19/01. 36. Hayes S. The pedorthic prescription. Ambulatory Foot Care Course, American Academy of Orthopaedic Surgeons, San Francisco, Calif.; 1987. 37. Helm PA, Walker SC, Pullium GF. Recurrence of neuropathic ulcerations following healing in a total contact cast. Arch Phys Med Rehabil. 1991;72:967-970. 38. Centers for Disease Control, Disease Prevention and Health Promotion. Economic aspects of diabetes services and education. US Department of Health and Human Services, Atlanta, Ga. Selected annotations. 1992. 39. Lavery LA, Lavery DC, Quebedeaux-Farnham TL. Increased foot pressures after great toe amputation in diabetes. Diabetes Care. 1995;18:1460-1462. 40. Murray HJ, Boulton AJM. The pathophysiology of diabetic foot ulceration. Clin Podiatr Med Surg. 1995;12:41-61. 41. Frykberg RG, Kozak GP. The diabetic Charcot foot. In: Kozak GP, Hoar CS, Rowbotham JL, et al, eds. Management of Diabetic Foot Problems. Philadelphia, Pa.: WB Saunders Company; 1994:103-112. 42. Janisse DJ. Prescription insoles and footwear. Clin Podiatr Med Surg. 1995;12:41-61. 43. Pedorthic Footwear Association. Introduction to Pedorthics. Columbia, Md.; 1998. 44. Cohen MM, Brietstein RJ, Brill L. Wound Care Q&A: improve your treatment of Charcot foot, part II. Podiatry Today Magazine. 2000;Jul/Aug:79-81. 45. Bower AC, Allman RM. Pathogenesis of the neuropathic joint: neurotraumatic vs. neurovascular. Radiology. 1981:139-349. 46. Sanders LJ, Frykberg RG. Diabetic neuropathic osteoarthropathy: Charcot foot. In: Frykberg RG, ed. The High Risk Foot in Diabetes Mellitus. New York, NY: Churchill Livingston; 1991:297-338. 47. Greene DA, Feldman EL, Stevens M. Neuropathy in the diabetic foot: new concepts in etiology and treatment. In: Levin ME, O?Neil LW, Bowker JH, eds. The Diabetic Foot, 5th ed. St. Louis, Mo.: Mosby Year Book; 1993:135. 48. Eichenholtz SN. Charcot?s Joints. Springfield, Ill.: Charles C. Thomas; 1966. 49. Johnson JE. Surgical reconstruction of the diabetic Charcot foot and ankle. Foot and Ankle Clinics. 1997;2(1):37-55. 50. Johnson JE, O?Brien TS, Hart TS, et al. Reconstruction of the Charcot?s foot and ankle: an outcome study of long-term results. Abstract presented at the American Orthopedic Foot and Ankle Society 12th Annual Summer Meeting; June 27-30, 1996; Hilton Head, SC. 51. Banks AS. A clinical guide to Charcot foot, In: Kominsky SJ, ed. Medical and Surgical Management of the Diabetic Foot. Baltimore, Md.: Mosby; 1994:115-143. 52. Krause JO, Brodsky JW. The natural history of type 1 midfoot neuropathic feet. Foot and Ankle Clinics. 1997;2(1):1-22. 53. Frykberg RG, Mendeszoom ER. Charcot arthropathy: pathogenesis and management. Wounds. 2000;12(6 Suppl B):35B-42B. 54. Waters RL, Perry J, Antonelli D, et al. Energy cost of walking of amputees: the influence of length of amputation. Am J Bone Joint Surg. 1976;58A:42-51. 55. Marks RM. Mid-foot/mid-tarsus amputations. Amputations. Foot and Ankle. 1999;4(1):1-16. 56. Campbell JT. Syme?s, Boyd?s, Chopart?s and Pirogoff?s amputations. Amputations. Foot and Ankle. 1999;4(1): 39-62. 57. Lehman JF, Price R, Koon G. Worth the weight: prosthetic mass and gait. Biomechanics. 1998;12:15-20. Additional Resources Valmassy RL. Clinical Biomechanics of the Lower Extremities. St. Louis, Mo.: Mosby Yearbook; 1996:365-366. Armstrong DG, Abu-Rumman PL, Nixon, BP, Boulton, AJM. Continuous activity monitoring with persons at high risk for diabetis-related extremity amputation. J Amer Pod Med Assoc. 2001;91(9):451-455.







Post new comment