An Overview of Neonatal and Pediatric Wound Care Knowledge and Considerations

Author(s): 
Mona Mylene Baharestani, PhD, ANP, CWOCN, CWS

Apaucity of pediatric wound care research is available upon which to guide practice; few wound care products have been studied in this population.1-3 This problem is compounded further by the ethical and litigious issues involved in carrying out research in this vulnerable population, leaving clinicians without an evidence base from which to render care. In fact, it is not unusual for skin care regimens to be based on individual or institutional preference and routine.4 Most papers on wound care in neonates and children are anecdotal or are discussions of wound healing principles and clinical practice guidelines for adults.1 Research data regarding the safety and clinical efficacy of wound care dressings, drugs, and adjunctive treatments in neonates and children are needed.3,5

Although they follow the same wound healing trajectory as adults, wounds in neonates and children typically exhibit faster rates of closure.6-8 Fibroblasts are present in greater numbers, collagen and elastin are more rapidly produced, and granulation tissue forms more quickly compared to adults.8,9 In fact, rapid, uncomplicated wound healing requiring limited healthcare professional intervention is the “normative expectation” in pediatrics.10 This expectation of rapid, uneventful healing and innate age-related integumentary resiliency has, in part, resulted in the lack of wound care knowledge transfer to the pediatric population.10 Pieper et al’s1 recent study of 13 home care agencies found that while children represented 3% of all visits and 17% of children had wounds, basic principles of wound care were not implemented into practice. Pressure ulcers and open surgical wounds among this pediatric population often were cleansed with hydrogen peroxide, household soap, or povidone-iodine — 44% were treated with dry gauze and 19% with normal saline dampened gauze.1 Yet, more than 90% of the home care nurses interviewed for this study described the pediatric wound care as appropriate.1 Similarly, a survey11 among 104 neonatal intensive care units (NICUs) in the US found that less than 25% had wound care protocols in place. A survey of 13 NICUs in the UK reported wound care practices to be wide and varied with neither written policy nor guidelines for staff.12 In fact, 32% of wounds were either left open to air or covered with dry dressings, with the prevailing view of staff participating in the study that plastic surgery would cure the wound at a later time.12 Although eight of the units surveyed had access to wound specialists, only one unit reported use of this specialty.12 Baker et al’s13 US survey of 305 NICUs also reported a lack of consensus on skin care practices, with less than 30% of those interviewed agreeing on how to treat skin breakdown in micro-preemies. As a result, wounds were treated with hydrogen peroxide, exposed to air, or “allowed to heal” without intervention.1

The purpose of this overview is to illuminate key anatomical/structural differences in neonatal skin as it pertains to percutaneous absorption, and tolerance of adhesives to foster anatomically/physiologically based inquiry when selecting prevention and treatment modalities; and to review the evidence for commonly encountered wound types.

References: 

1. Pieper B, Templin T, Dobal M, Jacox A. Prevalence and types of wounds among children receiving care in the home. Ostomy Wound Manage. 2000;46(4):36–42.
2. Siegfried EC, Shah PY. Skin care practices in the neonatal nursery: a clinical survey. J Perinatology. 1999;19(1):31–39.
3. Irving V. Caring for and protecting the skin of pre-term neonates. J Wound Care. 2001;10(7):253–256.
4. Malloy-McDonald MB. Skin care for high risk neonates. J WOCN. 1995;22:177–182.
5. Irving V. Skin problems in the pre-term infant: avoiding ritualistic practice. Professional Nurse. 2001;17(1):63–66.
6. Bale S, Jones V. Caring for children with wounds. J Wound Care. 1996;5(4):177–180.
7. Garvin G. Wound healing in pediatrics. Nurs Clin North Am. 1990; 25:181–192.
8. Wysocki AB. Anatomy and physiology of skin and soft tissue. In: Bryant RA, ed. Acute and Chronic Wounds: Nursing Management, 2nd Edition. St. Louis, Mo: Mosby;2002.
9. The Tendra Academy®. Report from an independent multidisciplinary advisory group. Issues in paediatric wound care: minimizing trauma and pain. April 2004. Molnlycke Health Care, Inc., Norcross, Ga.
10. Baharestani MM, Pope E. Chronic wounds in neonates and children. In: Krasner D, Rodeheaver GT, Sibbald GT, eds. Chronic Wound Care: A Clinical Source Book for Healthcare Professionals, 4th Edition. Malvern, Pa: HMP Communications;2007:679–693.
11. Munson KA, Bare DE, Hoath SB, Visscher MO. A survey of skin care practices for premature low birth weight infants. Neonatal Network. 1999;18(3):25–31.
12. Irving V. Neonatal iatrogenic skin injuries: a nursing perspective. J Neonatal Nurs. 1999;5(5):10–13.
13. Baker SF, Smith BJ, Donohue PK, Gleason CA. Skin care management practices for premature infants. J Perinatology. 1999;19(6 Pt 1):426–431.
14. Rustogi R, Mill J, Fraser JF, Kimble RM. The use of Acticoat™ in neonatal burns. Burns. 2005;31(7):878–882.
15. Keener KE. The surgical neonate. In: Wise BV, McKenna C, Garvin G, Harmon BJ, eds. Nursing Care of the General Pediatric Surgical Patient. Gaithersburg, Md: Aspen Publishers, Inc;2000.
16. Lund CH, Tucker JA. Adhesion and newborn skin. In: Hoath SB, Maibach, HI, eds. Neonatal Skin Structure and Function, 2nd edition. New York, NY: Marcel Deckker, Inc; 2003.
17. Eichenfield L, Hardaway C. Neonatology dermatology. Curr Opin Pediatr. 1999;11(5):471–474.
18. Campbell JM, Banta-Wright SA. Neonatal skin disorders: a review of selected dermatologic abnormalities. J Perinat Neonat Nurs. 2000;14(1):63–83.
19. Garvin G. Wound and skin care in PICU. Crit Care Nurs Q. 1997;20(1):62–71.
20. Malloy MB, Perez-Woods RC. Neonatal skin care: prevention of skin breakdown. Pediatric Nurs. 1991; 17(1):41–48.
21. Kuller JM, Lund CH. Assessment and management of integumentary dysfunction. In: Kenner C, Brueggemeyer A, Gunderson LP, eds. Comprehensive Neonatal Nursing: A Physiologic Perspective. Philadelphia, Pa: WB Saunders;1993.
22. Noonan C, Quigley S, Curley MAQ. Skin integrity in hospitalized infants and children — a prevalence survey. J Ped Nurs. 2006;21(6):445–453.
23. McLane KM, Bookout K, McCord S, McCain J, Jefferson LS. The 2003 national pediatric pressure ulcer and skin breakdown prevalence survey: a multisite study. J WOCN. 2004;31(4):168–178.
24. Association of Women’s Health, Obstetric and Neonatal Nurses (AWHONN). Neonatal skin care. Evidence-based clinical practice guideline. Washington, DC: Association of Women’s Health, Obstetric and Neonatal Nurses (AWHONN); January 2001.
25. Lund C. Prevention and management of infant skin breakdown. Nurs Clin N Am. 1999;34(4):907–920, vii.
26. Report from an independent advisory group. Issues in neonatal wound care minimizing trauma and pain. The Tendra Academy®. June 2005. Molnlycke Health Care, Inc., Norcross, Ga.
27. Irving V. Reducing the risk of epidermal stripping in the neonatal population: an evaluation of an alcohol free barrier film. J Neonatal Nurs. 2001;7:5–8.
28. 3M Health Care. 3M Cavilon No-Sting Barrier Film (brochure). Saint Paul, MN;2000.
29. Irving V, Bethell E, Burton F, on behalf of a Neonatal Advisory Group. Neonatal wound care: minimizing trauma and pain. Wounds UK. 2006;2(1):33–41.
30. Irving V. Wound care for preterm neonates. Infant. 2006;2(3):102–106.
31. McCullen KL, Pieper B. A retrospective chart review of risk factors for extravasation among neonates receiving peripheral intravascular fluids. J WOCN. 2006;33(2):133–139.
32. Wilkins C, Emmerson A. Extravasation injuries on regional neonatal units. Arch Dis Child Fetal Ed. 2004;89:F274–F275.
33. Shenaq SM, Abbase EH, Friedman JD. Soft-tissue reconstruction following extravasation of chemotherapeutic agents. Surg Oncol Clin N Am. 1996;5(4):825–845.
34. Flemmer L, Chan J. A pediatric protocol for management of extravasation injuries. Pediatr Nurs. 1993;19(4):355–358,424.
35. Thomas S, Rowe HN, Keats J, Morgan RJH. The management of extravasation injury in neonates. Available at: www.worldwidewounds.com.1997. Accessed January 11, 2006.
36. McCord S, Bookout K, McLane K, Helmrath M. Use of silver dressing with neonatal abdominal evisceration. Poster presented at the 36th Wound, Ostomy, Continence Nurses (WOCN) Annual Conference. Tampa, Fla. June 2004.
37. Simon A, Sofka K, Wiszniewsky G, et al. Wound care with antibacterial honey (Medihoney) in pediatric haematology-oncology. Support Care Cancer. 2006;14(1):91–97.
38. Linder N, Davidovitch N, Reichman B, et al. Topical iodine-containing antiseptics and subclinical hypothroidism in preterm infants. J Ped. 1997;131(3):434–439.
39. Hansbrough JF, Hansbrough W. Pediatric burns. Pediatr Rev. 1999;20(4):117–123.
40. Mandal A. Paediatric partial-thickness scald burns — is Biobrane the best treatment available? Int Wound J. 2007;4(1):15–19.
41. Gotschall CS, Morrison MI, Eichelberger MR. Prospective, randomized study of the efficacy of Mepitel® on children with partial-thickness scalds. J Burn Care Rehab. 1998;19(4):279–283.
42. Frieden IJ. Aplasia cutis congenita: a clinical review and proposal for classification. J Am Acad Dermatol. 1986;14(4):646–660.
43. Valencia IC, Falabella AF, Schahner LA. New developments in wound care for infants and children. Pediatr Ann. 2001;30(4):211–218.
44. Sargent LA. Aplasia cutis congenita of the scalp. J Pediatr Surg. 1990;25:1211–1213.
45. Bello YM, Falabella AF, Schachner LA. Epidermolysis bullosa and its treatment. WOUNDS. 2001;13(3):113–118.
46. Falabella AF, Valencia IC, Eaglstein WH, Schachner LA. Tissue-engineered skin (Apligraft) in the healing of patients with epidermolysis bullosa wounds. Arch Dermatol. 2000;136:1225–1230.
47. Rottman SJ, Glat PM. the use of a biologic tissue matrix (Integra Bilayer Matrix Wound Dressing) in the treatment of recessive dystrophic epidermolysis bullosa pseudosyndactyly deformity. WOUNDS. 2006;18(11):315–321.
48. Curley MAQ, Razmus IS, Roberts KE, Wypij D. Predicting pressure ulcer risk in pediatric patients —the Braden Q scale. Nurs Res. 2003;52(1):22–31.
49. Baharestani M, Vertichio R, Higgins MB, Kurot M, May B. A neonatal and pediatric evidence-linked pressure ulcer and skin care performance improvement initiative. Poster abstract presented at the Symposium on Advanced Wound Care and Medical Research Forum on Wound Repair. April 21–24, 2005. San Diego, Calif.
50. Okamoto GN, Lamers JV, Shurtleff DB. Skin breakdown in patients with myelomengocele. Arch Phys Med Rehab. 1983;64:20-23.
51. Willock J, Hughes J, Tickle S, et al. Pressure sores in children — the acute hospital perspective. Tissue Viabil Soc. 2000;10(2):59–62.
52. Black J, Baharestani MM, Cuddigan J, et al. National Pressure Ulcer Advisory Panel’s updated staging system. Adv Skin Wound Care. 2007; In press.
53. Baharestani MM, Ratliff C, and the National Pressure Ulcer Advisory Panel. Pressure ulcers in neonates and children: an NPUAP white paper. Adv Skin Wound Care. 2007;20(4):208–220.
54. Smith ZK. Adapting a soft silicone dressing to enhance infant outcomes. Ostomy Wound Manage; 2006;52(4):30–32.
55. Baharestani MM. Pressure ulcers in special populations: neonates and pediatrics. In: Baranoski S, Ayello E, eds. Wound Care Essentials: Practice Principles, 2nd Edition. Philadelphia, Pa: Lippincott Williams & Wilkins.2007: In press.
56. Hoath SB, Narendran V. Adhesives and emollients in the preterm infant. Semin Neonatol. 2000;5(4):289–296.
57. Suraseranivongse S, Kaosaard R, Intakong P. A comparison of postoperative pain scales in neonates. Br J Anaesth. 2006;97(4):540–544.
58. Quigley SM, Curly MAQ. Skin integrity in the pediatric population: preventing and managing pressure ulcers. JSPN. 1996;1(1):7–18.
59. Darmstadt GL, Dinulos JG. Neonatal skin care. Ped Clin NA. 2000;47(4):757–782.
60. Taquino LT. Promoting wound healing in the neonatal setting: process versus protocol. J Perinat Nurs. 2000;14(1):104–118.
61. Hagelgans NA. Pediatric skin care issues for the home care nurse. Pediatr Nurs. 1993;19(5):499–507.
62. Packard S, Douma C. Skin care. In: Cloherty JP, Eichenwald EC, Stark AR, eds. Manual of Neonatal Care, 5th edition. Philadelphia, Pa: Lippincott Williams & Wilkins;2004.
63. Atkins J, Irving V, Young T. Development of a wound care policy for neonates. (Poster). Available from author.
64. Harris Ah, Coker KL, Smith CG, Uitvlugt N, Doctor B. Case report of a pressure ulcer in an infant receiving extracorpreal life support: the use of a novel mattress surface for pressure reduction. Adv Neonatal Care. 2003;3(5):220–229.
65. Moushley R, Meadows L. Burn care of children. In: Wise BV, McKenna C, Garvin G, Harmon BJ, eds. Nursing Care of the General Pediatric Surgical Patient. Gaithersburg, Md: Aspen Publishers, Inc;2000
66. Fell J. Versiva dressing in the management of a severe extravasation injury in a premature baby. (Poster) 2002. Available from author.
67. Caniano DA, Ruth B, Teich S. Wound management with vacuum-assisted closure: experience in 51 pediatric patients. J Ped Surg. 2005;40:128–132.
68. Spooner J. Use of a papain, urea enzymatic debriding ointment on a pediatric patient with an intravenous infiltrate burn. (Poster) Available from author.
69. Samaniego I. Developing a skin care pathway for pediatrics. Derm Nurs. 2002;14(6):393–396.
70. Hickey K, Vogel LC, Anderson CJ. Pressure ulcers in pediatric spinal cord injury. Topics Spinal Cord Injury Rehabil. 2000;6(Supp):85–90.
71. Royal College of Nursing. Clinical practice guidelines: the recognition and assessment of acute pain in children: technical report. London, UK: RCN;2002.
72. American Academy of Pediatrics, Canadian Paediatric Society. Prevention and management of pain in the neonate: an update. Pediatrics. 2006;118(5):2231–2241.



Post new comment

  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
  • Use to create page breaks.

More information about formatting options

Image CAPTCHA
Enter the characters shown in the image.